- Listen to James Sharpe talking about his work.
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Mid-gestation mouse embryo
The new technique of Optical Projection Tomography (OPT) helps to reveal the internal structures of stained whole embryos and small pieces of tissue without the need for cutting sections. The mouse embryo shown here has been stained to show parts of the nervous system in green, the floor of the spinal cord and other tissue in blue and the heart in red. Unstained tissue appears grey. The OPT technique enables different elements of the staining patterns to be revealed in more detail using the computer to selectively remove overlying tissue. This process can be observed in the accompanying on-screen animation.
Optical Projection Tomography image by James Sharpe.
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