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Bone from an osteoporosis sufferer

The world’s first fully in-focus scanning electron microscope image. Being completely focused in every plane allows better discrimination of the features at each and every point on the surface of the specimen. This image illustrates the action of osteoclasts on a vertebral bone in an osteoporosis sufferer. Osteoclasts are the cells that eat away the bone. To achieve focus at all focal depths a computer resolves the information from many different individually-focused images creating this one unique and striking image. The colour is generated by coding the information coming from three electron detectors as red, green or blue in order to create the composite colour effect. The colour hue shows orientation, and colour intensity shows the slope of the surface.
Credit: Alan Boyde