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Biomedical resource and technology development grants

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Biomedical resource/technology development grants are intended to provide support for researchers wishing to establish a new resource/technology or to refine and maintain an existing resources/technology (including databases and collections) for the benefit of the wider scientific community.

Applications should take into account the needs of the wider research community and be supported by evidence of need for the resource/technology. Evidence of access and data management policies that enable optimal use of these resources/technologies is required, together with a business plan that addresses sustainability in the medium to long term. Applicants should also demonstrate how the resource/technology would add value to Wellcome Trust-funded research.

Applicants proposing to submit applications in support of cohorts should contact the Trust for further guidance before submitting their applications.

Applications for biomedical resource/technology development grants will be considered annually (alongside multi-user equipment grant applications) at a specially convened committee.

What's included

Up to five years' support is available, and expenses may include:

  • salaries for staff (for biomedical resource applications, staff must be necessary to run and/or manage the central resource. Support for experimental research personnel will only be considered for technology development grants).
  • materials and consumables required for establishing and maintaining the resource/technology
  • the purchase and maintenance of animals
  • the purchase and essential running and maintenance costs of equipment
  • collaborative travel and attendance at scientific meetings to publicise the resource/technology.

The maximum amount awarded for a successful application is anticipated to be £1.5m. Please contact the Trust if your proposal may exceed £1.5m.

Please note that the Trust would normally expect an institutional contribution towards the purchase and/or management of major items of equipment, where these are central to the proposal.


This scheme is open to applicants in the UK who meet our standard eligibility criteria and have a track record in obtaining grant funding.

Researchers in low- or middle-income countries may be eligible to apply if they have a track record of Trust funding or if they can demonstrate that they have established a strong track record of independent research accomplishment.

Application process

Preliminary application stage

Please use WT Grant Tracker to complete your preliminary application (you will need to select the ‘Biomedical resources grant’ or ‘Technology development grant’ form).

You will be required to provide a supporting statement from the host institution outlining their commitment to the resource/technology development.

You are advised to refer to the ‘Application Advice’ section below for points to consider when preparing your application.

Completed preliminary application forms will be assessed and, if shortlisted, you will then be invited to submit a full application.

Full application stage

Full applications submitted for the published deadline will be sent out for peer review.

Selected unattributed referee comments will be fed back to applicants before applications are considered by a specially convened committee.

Please note that the Trust does not normally accept the resubmission of unsuccessful applications.

Application advice

Points to consider when preparing your preliminary and full applications include:

  • the potential impact and importance of the biomedical resource/technology development should be clearly articulated
  • those involved in the assessment of an application will need to be convinced that there is a genuine demand for the resource/technology and that it will meet that demand (evidence of consultation with potential user groups should be provided)
  • whether similar collections/technologies exist elsewhere and, if so, whether these will be complemented by the proposed resource/technology
  • the feasibility of establishing the resource/technology may be demonstrated by the inclusion of pilot data
  • the quality standards that will be applied to the resource/technology and how it will be evaluated
  • issues of interoperability for applicants applying to establish and/or maintain databases
  • how the resource/technology will be promoted and/or disseminated
  • demonstrate that the resource/technology development will be appropriately managed and explain how requests for access will be prioritised
  • plans for the resource/technology at the conclusion of the proposed grant period - you will need to submit a convincing business plan to demonstrate sustainability in the medium to long term
  • that a sound plan for data management and sharing has been constructed, to enable optimal use of the resource/technology by the research community.

Assessment criteria

Both preliminary and full applications will be assessed using the following criteria:

  • track record of the applicants and coapplicants and their ability to deliver
  • how the resource/technology development will enhance existing Trust investments in strategic areas of interest and add value to Trust-funded research
  • how the resource/technology development will enhance the scientific programmes of the applicants and/or the research community
  • the regional and national (and international, if appropriate) context of the application
  • plans for longer-term sustainability
  • evidence of community need
  • plans for data management and sharing.


This is an annual competition.

  • Preliminary application deadline: Friday 20 November 2015 (5pm)
  • Invited full application deadline: Monday 29 February 2016 (5pm)
  • Committee review: 16 June 2016

Late applications will not be accepted at any stage.

Contact us

About your eligibility, the application process or general queries about grants

About the content of your project or proposal

About our online application system

Current award holders

Details of the Biomedical resource grants awarded in 2014

Professor Michael P Eddleston, University of Edinburgh
A large-animal critical-care laboratory with 24/7 specialist anaesthesia support - a UK national resource for scientists working in translational research

Dr Aiden Mark Emery, Natural History Museum
SCAN: the Schistosomiasis Collections at the Natural History Museum

Dr Paul Flicek, EMBL at Hinxton
The International Genome Sample Resource

Dr Gerrit Kleijwegt, EMBL at Hinxton
Protein Data Bank in Europe - an integrated resource for 3D molecular and cellular structure

Dr Joao Pedro De Magalhaes, University of Liverpool
Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing

Professor Martin C J Maiden, University of Oxford
PubMLST: public databases for molecular typing and microbial genome diversity

Professor Jeremy C Mottram, University of Glasgow
In vivo screening resource to support drug development in parasitic disease

Dr Charles Joseph O'Kane, University of Cambridge
Professor James Douglas Armstrong, University of Edinburgh
Dr Gregory S Jefferis, MRC Laboratory of Molecular Biology
Dr Helen Parkinson, EMBL at Hinxton

Virtual Fly Brain: a global informatics hub for Drosophila neurobiology

Dr Raymond T O'Keefe, University of Manchester
The yeast non-coding RNA functional genomic resource

Professor Stephen G Oliver, University of Cambridge
Enhancing the fission yeast model organism database POMBASE and extending the benefits of community annotation

Professor Christine A Orengo, University College London
FunVar: impacts of genetic variations on protein functions and functional pathways

Professor Timothy D Spector, King’s College London
TwinsUK (2015-17): an epidemiological and genomic resource

Professor Michael J E Sternberg, Imperial College London
Development and dissemination of a community tool for structure-based annotations of proteins in disease networks

Details of the Biomedical resource grants awarded in 2013

Professor Geoffrey J Barton, School of Life Sciences, University of Dundee
Extending the Jalview Resource for Biological Sequence Alignment and Analysis

Professor Ian N Clarke, University of Southampton
A global Chlamydia trachomatis biobank integrated with a comprehensive genome sequence database

Dr Majid Ezzati, Imperial College London
A global database on cardiovascular risk factors

Professor Matthew J Guille, University of Portsmouth
The European Xenopus Resource Centre (EXRC)

Mr Henning Hermjakob, EMBL at Hinxton

Professor Deborah A Lawlor, University of Bristol
'The Born in Bradford (BiB) Study’: an international biomedical resource for exploring genetic and early life determinants of health and development in a deprived multi-ethnic population

Professor Richard J Piercy, Royal Veterinary College
Developing and phenotyping a colony of dogs with dystrophin-deficient muscular dystrophy: a strategic resource for UK-based research into Duchenne muscular dystrophy

Professor Haroun Shah, Public Health England
Creation of an e-resource centre to underpin the provision and use of Type and reference strains of human pathogens

Professor R Angus Silver, University College London
The Open Source Brain Repository: enabling the collaborative development of open and accessible models for neuroscience

Professor Christopher Thompson, University of Manchester
REMI-seq: generation of a genome-wide mutant resource for Dictyostelium functional genomics

Details of the Biomedical resource grants awarded in 2012

Dr David Aanensen, Imperial College London
MiPGR - the Microbial Population Genomics Resource

Dr Elspeth Bruford, European Bioinformatics Institute, Wellcome Trust Genome Campus
The nomenclature of human and vertebrate genes

Dr David Cavanagh, University of Edinburgh
The European Malaria Reagent Repository

Professor Andrew Copp, University College London
Professor Susan Lindsay, Newcastle University

Human Developmental Biology Resource (HDBR): an embryonic and fetal tissue bank for the new genetics technologies

Professor Ten Feizi, Imperial College London
Carbohydrate microarray facility for biomedical exploitation

Dr Paul Flicek, European Bioinformatics Institute, Wellcome Trust Genome Campus
The DGVa - a database for genomic structural variation

Professor Anthony Harmar, University of Edinburgh
guidetopharmacology.org - a peer-reviewed online resource giving information on drugs and their targets

Dr Christiane Hertz-Fowler, University of Liverpool
Integrated bioinformatics resources for kinetoplastid pathogens

Professor So Iwata, Imperial College London
The Membrane Protein Laboratory at Diamond Light Source

Professor Peter Kaiser, University of Edinburgh
The National Avian Resource Facility

Dr Gos Micklem, University of Cambridge
InterMine and humanMine - enhancing the biomedical relevance of model organisms and enabling other data mining projects

Professor Michael Overduin, University of Birmingham
HWB NMR: a national resource for biomolecular research

Professor Colin Palmer, University of Dundee
The Tayside Bioresource: Leveraging Electronic Medical Records to deliver personalised medicine

Professor Timothy Spector, King’s College London
TwinsUK (2012-2014) - an epidemiological and genomic resource

Wellcome Trust, Gibbs Building, 215 Euston Road, London NW1 2BE, UK T:+44 (0)20 7611 8888