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Big Picture

No more insulin: Neonatal diabetes

Young girl injecting insulin
We spoke to Professors Andrew Hattersley and Frances Ashcroft about their research into diabetes, and met some people affected by the condition whose lives have been transformed as a result of this research.

Neonatal diabetes is a rare but severe form of the disease that occurs early in life. Children affected often have to undergo a life of daily insulin injections and strict diet monitoring.

However, thanks to scientific research, many patients can now take well-known drugs called sulphonylureas instead. This change is thanks to the work of Professors Andrew Hattersley and Frances Ashcroft, who found that the condition was caused by a genetic mutation that disrupted part of the insulin-secreting pathway, and could be treated with these drugs.

Find out more by watching the video below.

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Running time: 5 min 16 s
Read the transcript [PDF 148KB]

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