Genomic Epidemiology of Malaria
29 August-4 September 2010
Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand
Deadline for applications: 7 May 2010
Course overview
Advances in high-throughput genome sequencing and genotyping technologies are revolutionizing the way we study infectious disease in natural populations. This course will teach researchers to apply new genomic tools and analyses to malaria epidemiology, with the goal to be able to detect and use information about natural genetic variation in the parasite, vector and host genome to understand and control disease.
The course will cover key concepts in genome variation and population genetics, current and emerging sequencing and genotyping technologies to detect variation, and analysis tools for interpreting their data outputs. Concepts and technologies will be presented in the context of real-world applications, like using genetic variation for surveillance of anti-malarial drug and insecticide resistance.
Programme
Topics will include:
- high-throughput sequencing using Illumina technology
- analysis of genomic features and identification of variation within and across genomes and populations
- large scale genotyping platforms and methodologies
- performing genome-wide association studies
- relevant statistical analyses
- population genetics
- considerations for epidemiological study design
- use of high-throughput sequencing technology in lab-based studies of drug resistance
- applications of genomics to malaria elimination.
The programme will comprise lecture and practical sessions in which relevant analysis tools and software will be applied to relevant, real datasets from ongoing studies in genomic epidemiology of malaria. Practical sessions will illustrate the ideas presented in the lectures. Wherever possible, open source software will be used to facilitate implementation of skills after the course.
Scientific Programme Committee
- Dominic Kwiatkowski (Wellcome Trust Sanger Institute/Oxford University, UK)
- Bronwyn MacInnis (Wellcome Trust Sanger Institute, UK)
- Olivo Miotto (Oxford University, UK/Mihadol University, Thailand)
- Matthew Berriman (Wellcome Trust Sanger Institute, UK)
- Chris Newbold Wellcome Trust Sanger Institute/Oxford University, UK)
How to apply
Prerequisites
Space for the course is limited. Priority will be given to researchers working in malaria-endemic regions who convey how the course focus – applying large-scale genome science to malaria epidemiology and control – will be of practical relevance to their current or planned research.
Cost
The workshop is subsidised by the Wellcome Trust and is free to attend for clinical and academic (i.e. non-commercial) applicants.
Bursaries
Bursaries are available for non-commercial applicants to cover travel and accommodation costs. These are subject to a selection process and are awarded on merit. The amount awarded will depend on the number of applicants.
Bursary application information, plus terms and conditions
Applications
Applicants will be required to complete an application form containing a 300-word outline of the relevance of the course to their research/clinical work. Please note that documentation supporting their application will be required from the applicant's supervisor/head of department.
To submit an application please either email for an application form - advancedcourses@hinxton.wellcome.ac.uk – or download the form [Word 120KB] and our terms and conditions [Word28KB].
Applications can be accepted by post or email. Sponsors' supporting letters must be returned, signed, by fax or post under separate cover. NB incomplete applications will be rejected.
Applications and letters of support can be sent to:
Wellcome Trust Advanced Courses
Wellcome Trust Genome Campus
Hinxton
Cambridgeshire CB10 1SA
UK
F +44 (0) 1223 495130
E
advancedcourses@hinxton.wellcome.ac.uk
Deadlines
Deadline for applications: 7 May 2010