Malaria treatments

Mosquito
Artemisinin, an antimalarial drug based on a Chinese herb called qinghao (sweet wormwood), is having a major impact on the treatment of malaria.

Every year, malaria kills over 2.5 million people across the world - most of them children under five.

Wellcome Trust-funded scientists in South-east Asia, led by Professor Nick White, developed and tested the drug in the 1990s and have used it to treat malaria in Vietnam and Thailand with huge success.

  • Vietnam: In the early 1990s cases of malaria were running at 1.5 million a year with a mortality rate of 2500 per year. Using artemisinin, the death rate has dropped to around 100 per year.
  • Thailand: There are 100 000 refugees camped on the Thai/Burmese border. Since introducing artemisinin in 1994, cases of malaria have fallen by 90 per cent.
  • Artemisinin is now being used routinely in combination with other anti-malarial drugs, to delay the appearance of drug resistance. Artemisinin combination therapy (ACT) has been recommended by the World Health Organization as the best strategy for treatment of malaria.

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